CUstOm synthesis

For example: organic compounds, additives, polymers

Product catalog

3 categories of compounds

Chemical Analysis

Molecule of the month - NOrvaline

  • is a candidate drug for the treatment of Alzheimer’s disease
  • a arginase inhibitor which readily crosses the blood brain barrier, and reduces arginine loss in the brain.
  • Amyloid beta deposition is associated with L-arginine deprivation and neurodegeneration
  • mice treated with Norvaline display improved spatial memory, increased neuroplasticity-related proteins, and decrease in amyloid beta
  • is a non-protenogenic unbranched-chain amino acid
  • a natural component of an antifungal peptide of Bacillus subtilis
  • have received attention because they appear to be incorporated in some recombinant proteins found in E. coli
  • its biosynthesis has been examined
  • the incorporation of Nva into peptides reflects the imperfect selectivity of the associated aminoacyl-tRNA synthetase
  • in Miller-Urey experiments probing prebiotic synthesis of amino acids, norvaline, but also norleucine, are produced.
  • is known to promote tissue regeneration and muscle growth, and to become a precursor in the penicillin biosynthetic pathway